The eighth report from the Age-Related Eye Disease Study (AREDS), published in 2001 in the Archives of Ophthalmology, focused on the effects of high-dose supplementation with zinc, beta-carotene, and vitamins E and C on the loss of vision and the degeneration of the macula in individuals with age-related macular degeneration. This report presents the findings of a placebo-controlled, randomized clinical trial conducted by the Research Group for Eye-Related Disease Study.
The effect of zinc supplementation on glycemic control and serum zinc levels in patients with type 2 diabetes was studied by SS Al-Sharbatti and RA Al-Maroof in 2006.
32-26:1(21). Nutr Coll Am J. The mechanisms of action and experimental assessment of oral zinc supplementation in rehydration solutions were studied by KU, Rehman S, Perveen W, Altaf et al.
The potential antioxidant effects of chromium and zinc supplementation in people with type 2 diabetes mellitus were investigated in a study published in the American Journal of Nutrition. The researchers, A. Kerkeni, JM Matheau S, Mahjoub N, Zouari AM, Roussel RA, and Anderson, examined the impact of these supplements on individuals with diabetes.
The treatment of attention deficit hyperactivity disorder in adolescents and children involves the use of psychopharmacological methods such as amphetamine, essential fatty acids, moderate zinc, and acid. This was discussed in the article by N. Votolato SM, Pinkham LE, and Arnold, published in 2000 in the Psychopharmacology of Adolescents and Children Journal, with the reference number 10:111-117.
Basnet S, et al. A randomized controlled trial of zinc as supplementary treatment for severe pneumonia in young children. Pediatrics. 2012;129(4):701-8.
The publication titled “Am J Med. 2001;111(2):103-108” presents a randomized experiment conducted by Belongia EA, Berg R, and Liu K. The purpose of this trial was to investigate the effectiveness of zinc nasal spray in treating upper respiratory illness among adults.
In a placebo-controlled, double-blind study, Kandil et al. Investigated the use of zinc sulfate in the treatment of attention deficit hyperactivity disorder (ADHD). The study was published in Psychiatry Biology Neuropsychopharmacology Progress in 2004 and had a sample size of 28 participants.
2000;19(2):205-221. Progress in Retinal Research. By P Sternberg Jr, M Wu, KC Nelson, and J Cai. DP Jones and safeguarding the retinal pigment epithelium. Prevention of oxidative harm and
Caruso TJ, Prober CG, Gwaltney JM. Treatment of naturally acquired common colds with zinc: a comprehensive evaluation. Clin Infect Dis. 2007;45(5):569-74.
E Cho, MJ Stampfer, JM Seddon, et al. Conducted a study to examine the relationship between the consumption of zinc and the risk of age-related macular degeneration. This study was published in Epidemiol Ann in 2001 and consists of 328-336 pages.
The United Nations. Dietary aspects in the pathogenesis of human essential hypertension. Nutrition. 2001;17(4):337-346.
8-34): 1(21-reb 6102 .DeM suhtlaH ,AG ybE .Ecafrus lanigiroto ezniZ dna yalpsan elbonkcol a ni segnellahcxe nocleB-ecapsocsiop ,gnilcirtsiDihcna niatnuocelpmoc a ni segnellahcxe fo seugitiravni nacirfA :laitirtsiH rehtonpoC-yasuecalp ,dihsniW ,nigebA regitcelferP.ElbaliavaJ.
In the Nutr Clin J Eur study, R-JM Brummer RW, Stockbrügger A, Badart-Smook BJ, and Geerling compared the nutritional status of recently diagnosed patients with inflammatory bowel disease to that of the general population. The study was conducted in 2000 and included a total of 54 participants (514-521).
A randomized clinical trial was conducted to evaluate the effects of topical zinc oxide/glycine treatment on oral herpes. The study was published in the journal Med Health Ther Altern in 2001, volume 7, issue 3, and the authors were A. D Riley, JC Godfrey NJ, HR Godfrey, and Godfrey.
Grahn BH, Paterson PG, Gottschall-Pass KT, Zhang Z. Zinc and the visual organ. J Am Coll Nutr. 2001;20(2 Suppl):106-118.
Hambridge M. Human zinc insufficiency. J Nutr. 2000;130(5S suppl):1344S-1349S.
In the study published in ENT Journal in 2000, the researchers conducted a trial to evaluate the effectiveness of a nasal gel containing zinc in treating common symptoms of the cold. The trial was placebo-controlled and double-blind. The authors of the study were E. Barron Sion, Nobel M, and Hirt.
The study ZENITH investigates the effect of zinc supplementation on the vitamin status of older and middle-aged European adults. It was published ahead of print on July 11, 2007 in the Nutr Clin J Eur. The authors of the study are E. Toti, A. Raguzzini, E. Azzini, M. Andriollo-Sanchez, A. Polito, and F. Intorre.
Krishnadev N, Meleth AD, Chew EY. Dietary supplements for age-related macular degeneration. Curr Opin Ophthalmol. 2010 May;21(3):184-9. Review.
Krowchuk DP. Managing acne. A useful handbook. Med Clin North Am. 2000;84(4):811-828.
In 2007, a study conducted by the AARP Health and Diet Institutes found a connection between the use of multivitamins and an increased risk of prostate cancer. The study was conducted nationally and involved researchers such as Subar A, ME, Wright KA, and Lawson.
In April 2007, a study published in the journal Experimental Eye Research reported a significant amount of zinc found in deposits located beneath the retinal pigment epithelium. The research team, led by Lengyel, Flinn, Peto, Linkous, Cano, Bird, and others, discovered this high concentration of zinc.
The SU.VI.MAX trial investigated the potential of antioxidant vitamin and mineral supplementation in preventing prostate cancer, as reported in the International Journal of Cancer in 2005 (Meyer et al., 2005, pp. 182-6).
In the Nutr Clin J Am, the study titled “Elderly home nursing in pneumonia and zinc serum” was conducted by DH Hamer, LS Leka, PF Jacques, BC Fine, GE Dallal, JB Barnett, and SN Meydani in 2007.
The research conducted by Meynadier J. Focuses on examining the efficiency and safety of two different treatment plans involving zinc gluconate for inflammatory acne. The findings were published in the European Journal of Dermatology in 2000, with the article being titled “Study on the effectiveness and safety of two regimens of zinc gluconate in treating acne characterized by inflammation.”
Miyata S. Zinc insufficiency in the senior population. Nippon Ronen Igakkai Zasshi. 2007;44(6):677-89.
The Dietary Reference Intakes (DRIs) for Vitamins: Recommended Intakes for Individuals, accessed on June 1, 2011, at the National Academy of Sciences.
The Lancet published a study in 2001, titled “Effects of Zinc Supplementation on Morbidity, Growth, and Pregnancy in Infants with Low Birthweight: A Randomised Placebo-Controlled Trial.” The authors of the study were GJ Fuchs, JG Hautvast, AH Baqui, GL Darmstadt, JM van Raaij, and SJ Osendarp.
In the study conducted by Chu AC and PP Papageorgiou, the effectiveness of a 5% benzoyl peroxide cream was compared to a cream containing zinc oxide and chloroxylenol (known as Nels cream) for the treatment of acne vulgaris. The trial was controlled, randomized, and double-blind, as reported in the Clin Exp Dermatol journal in 2000, with a reference to pages 16-20.
Patrick L. Nutrients and HIV: part 2 – vitamins A and E, zinc, B-vitamins, and magnesium. Alternative Medicine Review. 2000;5(1):39-51.
Polin: Fetal and Neonatal Physiology, 4th edition. Philadelphia, PA: Saunders Elsevier; 2011.
The study, published in the Annals of Internal Medicine in 2000, was a randomized, double-blind, placebo-controlled trial conducted by Prasad AS, Fitzgerald JT, Bao B, Beck FW, and Chandrasekar PH. The trial investigated the effects of zinc acetate treatment on the duration of symptoms and plasma cytokine levels in patients with the common cold.
Saper R, Rash R. Zinc: A necessary micronutrient. Am Fam Phys. 2008;79(9).
The effect of gestational zinc deficiency on pregnancy outcomes: a summary of observational studies and randomized trials on zinc supplementation in British nutrition journals, S101-S108 2 Suppl 85, by HP Sachdev and D Shah.
Shay NF, Manigan HF. Neurobiology of zinc-influenced food consumption. J Nutr. 2000;130:1493S-1499S.
Sinclair S. Male sterility: dietary and ecological factors to consider. Altern Med Rev. 2000;5(1):28-38.
Van Leeuwen R, Boekhoorn S, Vingerling JR, et al. Consumption of antioxidants and the risk of age-related macular degeneration. JAMA. 2005;294:3101-7.
The article “Male factor subfertility: possible causes and the influence of nutritional factors” was published in Fertility and Sterility in 2000, with the reference 73(3):435-442. The authors of the study are Wong Wy, Thomas CM, Merkus JM, Zielhuis GA, and Steegers-Theunissen RP.